Abstract
Several lines of evidences indicate that insulin affords short- and long-term neuroendocrine signals to modulate ingestive behavior. To further study a possible role of insulin in the control of food intake, male Wistar rats were subjected to various intra-third cerebro-ventricular applications of saline and insulin. Infusion of 2.0 mIU/rat of insulin at 1100 and 1900 decreased food intake in a 23.5 hr test period. Infusion of 0.5 mIU/rat of insulin between 1100 and 1200 decreased nighttime food intake during the 1st and 2nd days. Infusion of 2.0 mIU/rat/24 hr of insulin from osmotic minipumps decreased nighttime food intake throughout the active pump period and the effect persisted into the post-pump period. The results support the notion that insulin is involved in the regulation of food intake in the rat.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
