Abstract
The use of carbon monoxide as a direct reducing agent for the deoxygenation of terminal and internal epoxides to the respective olefins is presented. This reaction is homogeneously catalyzed by a carbonyl pincer‐iridium(I) complex in combination with a Lewis acid co‐catalyst to achieve a pre‐activation of the epoxide substrate, as well as the elimination of CO2 from a γ‐2‐iridabutyrolactone intermediate. Especially terminal alkyl epoxides react smoothly and without significant isomerization to the internal olefins under CO atmosphere in benzene or toluene at 80–120 °C. Detailed investigations reveal a substrate‐dependent change in the mechanism for the epoxide C−O bond activation between an oxidative addition under retention of the configuration and an SN2 reaction that leads to an inversion of the configuration.
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