Abstract

SummaryWhen purified Rauscher murine leukemia virus (RLV) was treated with sodium deoxycholate (DOC), an RNA-containing structure was released. This structure sedimented at the same rate as free viral RNA, displayed the same sedimentation heterogeneity, had little, if any, protein associated with it, and was solubilized by ribonuclease. It is, therefore, improbable that RLV RNA resides in a subviral structure which resembles nucleocapsids isolated from nononcogenic enveloped RNA viruses.

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