DENTINOGENIC GHOST CELL TUMOR: REPORT OF THREE NEW CASES

Abstract

This case series contributes with 3 new cases of dentinogenic ghost cell tumor (DGCT). Case 1 is a 44-year-old male patient with an expansive swelling in the posterior mandible of 2 years duration. It appeared as a well-defined mixed radiolucent-radiopaque (RL-RO) lesion associated with an unerupted first molar. Case 2 is a 22-year-old female patient referred for evaluation of a slow-growing asymptomatic swelling of unknown duration in the left posterior maxilla; it was a 4-cm well-defined unilocular RL-RO lesion causing resorption of adjacent molars and encroachment of the maxillary sinus. Case 3 is a 37-year-old male patient with an expansive well-defined radiolucency in the lower premolar region exhibiting root resorption. Microscopically, prominent ameloblastomatous proliferation with areas of ghost cells and dentinoid material were observed. The patients are under long-term follow-up with no signs of recurrence to date. DGCT should be microscopically distinguished from adenoid ameloblastoma with dentinoid.