Abstract

Objective To investigate the frequency of dentinogenic ghost cell tumor (DGCT) that has been submitted to microscopic examination from representative geographic regions of Brazil and to compare it with literature data. Study Design A retrospective study was conducted on biopsy results obtained from 1953-2016 at 6 Brazilian oral and maxillofacial pathology services. A total of 84,668 biopsy specimens were analyzed. Demographic data and histopathologic diagnosis were evaluated descriptively. A literature search was performed in PubMed/MEDLINE for articles about DGCT published from 1933-2017. Results A total of 10 cases of DGCT were identified across the sample. Most individuals were male patients (60%) and ranged in age from 12 to 64 years (mean, 27.6 years). The most frequent location was the mandible (66.3%), and most of patients were asymptomatic (62.5%). The literature review showed a higher frequency in Asia and North America, mainly affecting men in the fifth decade of life. Conclusion DGCT is an extremely rare lesion. Data regarding age of the Brazilian patients reported here differ with findings from cases reported elsewhere. Support: FAPEMIG

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