Abstract

Major depressive disorder (MDD) affects approximately 14.8 million adults in the United States, which is about 6.7 % of the US population. MDD impacts most activities of daily living, including oral hygiene practices and use of dental resources. This review article provides information related to underlying mechanisms of disease, diagnosis, and treatment so that dentists may best address patients’ dental concerns in the context of underlying depression. Laboratory and psychological screening tools are also discussed in relation to specific practice recommendations for managing patients with MDD as well as identifying patients with underlying symptoms who may be at risk for MDD.

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