Abstract
Prosthetic joint infection (PJI) is the 3rd most common cause of revision in total hip arthroplasty (THA) and the most common cause of revision in total knee arthroplasty (TKA). It is associated with high costs/economic burden and mortality. The most common cause of late PJI is due to haematogenous seedling of bacteria into the joint from remote site infection (RSI). Oral flora constitutes 6-13% of burden in PJI. Dental interventions in patients who have undergone joint replacement surgery (JRS) are at increased risk of PJI due to bacteraemia. Dental antibiotic prophylaxes (DAP) are known to reduce this bacteraemia which in-turn may reduce the incidence of PJI. Significant controversy exists Re: the role and use of DAP in preventing PJI. This narrative review attempts to answer key questions surrounding its use based on extensive literature review in English language over past four decades.
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