Abstract
Life is a fleeting fortune that passes leaving the rest of us transformed by memory. The scientific community is deeply saddened by the loss of Denise Barlow, who was a discoverer in mammalian genetics and gene regulation. Denise passed away peacefully in the presence of friends on October 21, 2017 and leaves behind a legacy of science and researchers inspired by her thinking. Denise studied biology at Reading University and obtained her PhD in Derek Burkes's laboratory at Warwick University in the UK. This was where her interest in developmental biology and especially that of the mammalian embryo arose. After studies of the interferon response, which led her to show that this important viral defense is first observed late in embryogenesis, she moved to London to work with Brigit Hogan at the Imperial Cancer Research Fund (ICRF) laboratories. She followed her desire to study gene expression in the early mouse embryo at a time when the genome sequences of mammals had not yet …
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