Abstract
Dengue outbreak has affected rural areas of Delhi-NCR, Haryana widely but it lacks in surveillance. High cases of dengue symptoms were reported in these regions whereas dengue symptoms have been a neglected issue in the anti-dengue drug development. Therefore, this study aims to analyze the status of the dengue infection, a rural issue of Delhi-NCR, Haryana and to identify the significance of dengue symptoms in anti-dengue drug development. The study was conducted when there is high chance of dengue infection i.e. from August 2015 to October 2015 at OPD Unit of PR Institute of Medical Science & Research, Delhi-NCR, Sonepat. It includes 158 patients from 24 rural areas of Haryana comprising both males and females from different age groups. Out of 20% cases, 6% were IgG-Positive, 9% were IgMPositive and 88% were NS1-Positive and rest 80% was normal. It includes 44% cases of thrombocytopenia. Badkhalsa village (28%), age group 18-24 (34%) and males (63%) reported cases of high infection. It was found that people with fewer platelet counts (Rai village) were not suffering from dengue whereas people with more platelet count reported dengue infection (Badkhalsa village). Interpretation & Conclusion: This study focuses on new research directions by highlighting the dengue symptoms importance in anti-dengue drug development also it is a first attempt to investigate the status of dengue, a rural issue of Delhi-NCR, Haryana and suggests that health authorities and people living in these regions should take initiatives for better health.
Highlights
Dengue, a mosquito-borne viral infection caused by four serotypes of dengue virus, transmitted by Aedes aegypti has become a global concern
If in an initial blood sample positive IgM and IgG tests are detected for dengue antibodies more probably it means that within the recent weeks, the person has been infected with dengue virus
Negative tests for IgM and/or IgG antibodies indicate that individual has no dengue infection and symptoms can be due to another cause or in an another case, it can be interpreted that antibody level is too low to be measurable
Summary
A mosquito-borne viral infection caused by four serotypes of dengue virus, transmitted by Aedes aegypti has become a global concern. More than 70% of people are at risk from Asia-Pacific region [1]. The dengue outbreak has affected a large area of. Cases from North India are less researched excluding Delhi. National Capital Region (NCR) of India includes more than a dozen districts of Haryana. Haryana is a North Indian state surrounding Delhi.
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