Abstract
We report a case series of dengue maculopathy with different ocular manifestations, managements, visual outcomes and sequelae of patients. All three cases were diagnosed to have dengue fever. Patients presented with symptoms of central scotoma (case 1 and case 3) and blurring of vision (case 2) on Day 9 of dengue fever. Fundus examination showed intra retinal haemorrhages (case 1 and case 2) and macula thickening (case 3). Optical coherence tomography (OCT) revealed macular thickening with intra retinal fluid (case 1) and diffuse retinal thickening (case 3), while in case 2, it had irregular ellipsoid line in OCT. Fundus fluorescence angiography (FFA) revealed parafoveal vasculitis. After treatment with systemic steroids, one patient had good visual outcome (case 2), while two others had a persistent central scotoma due to macula atrophy (case 3). Although it is a self limiting disease, but the mode of treatment is variable. Treatment with corticosteroids may hasten recovery of vision and prevent permanent visual impairment.
Highlights
Dengue fever is the most prevalent form of flavivirus in human which is transmitted by Aedes mosquitos [1]
We report a case series of dengue maculopathy with different ocular manifestations, managements, visual outcomes and sequelae of patients
In case 2, patient presented with significant vision loss, no abnormality detected on macula Optical coherence tomography (OCT), which is why we proceeded with Fundus fluorescence angiography (FFA), which showed perifoveal vasculitis
Summary
Dengue fever is the most prevalent form of flavivirus in human which is transmitted by Aedes mosquitos [1]. It is especially endemic in the tropics and warm regions of the world [2] [3]. The disease affects systemic which can cause mortality. It affects ocular as well as uveitis, maculopathy or optic neuritis [4]. Dengue maculopathy is the commonest ocular dengue diseases. The commonest ophthalmic symptoms of dengue maculopathy are blurring of vision, followed by scotoma, ocular pain and me-. The pathophysiology of dengue maculopathy is still unknown. We report ocular manifestation, management, visual outcome and sequelae of dengue maculopathy series cases in our center
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