Abstract
Background : Dengue is the most important emerging tropical viral disease in the world today. The World Health Organisation[WHO] estimates 50 million dengue infections occur annually and almost half the world’s population lives in countries where dengue infection is endemic 1 . Over the past several years, the epidemiological profile of dengue has been changing progressively and is currently characterized by an increase in the number of cases in children under 15 years of age 2 . Aim and objective : To evaluate and co-relate the hematological and biochemical data in children during the evolution of dengue fever and to predict the severity of the disease. Methods – It is a retrorespective study of 30 seropositive dengue cases below 18 years of age carried out in the period of Jan 2016 to Nov 2016. Their hematological and biochemical parameters were studied at Sri Balaji Action Medical Institute, New Delhi. Conclusion – Awareness, early recognition and early diagnosis are important for favorable out come. Hematological and biochemical profile are very helpful tools for disease monitoring and can be helpful in prediction of prognosis. Thrombocytopenia is a feature of dengue. DOI: 10.21276/awch.2017.1235
Highlights
The etiologic agent of dengue is the dengue virus [DENV], which belongs to the Flaviviridae family and the Flavivirus genus and has four serotypes [DEN-1, DEN – 2, DEN – 3, DEN – 4]
Dengue is the most common arthropod borne viral disease transmitted by mosquito of the genus Aedes aegypti and is one of the most significant diseases because it is associated with high rates of morbidity and mortality [1,2,3.]
Dengue shows a cyclical trend with a peak in September, October, November every year.It is a disease with a wide clinical spectrum and a wide variety of presentation, ranging from asymptomatic to an undifferentiated fever to the more severe forms such as severe dengue (SD) or Dengue Haemorrhagic Fever (DHF) [5]
Summary
Dengue is the most common arthropod borne viral disease transmitted by mosquito of the genus Aedes aegypti and is one of the most significant diseases because it is associated with high rates of morbidity and mortality [1,2,3.]. This disease currently represents a major public health issue especially in tropical and subtropical countries, where environmental conditions enable the development and proliferation of mosquito which breeds exclusively in domestic man made water receptacles . The intial febrile illness begins with rapid onset of high grade fever which is accompanied by retroorbital headache, severe myalgia , arthralgia, nausea, vomiting (more common in children) and general fatigue. Warning signs for deterioration are of utmost clinical importance.[2][8]
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