Abstract
Dengue infection, a mosquito-borne infectious disease in tropical and subtropical areas, has recently become an emerging global disease. The clinical course of dengue infection may be unfavorable in immunocompromised patients. In this report, we present a 16-year old female patient with acute myeloid leukemia who received allogeneic peripheral blood stem cell transplant five months prior to presentation. She was hospitalized at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, due to fever, headache, and myalgia for one day. During hospitalization, she developed capillary leakage syndrome and progressive thrombocytopenia. A diagnosis of dengue hemorrhagic fever was made and confirmed by positive dengue serology and polymerase chain reaction testing. She made a full recovery 14 days after hospitalization. Our case possibly acquired dengue virus from infected mosquitoes while visiting her relatives four days before her present illness. In conclusion, this is the first reported case of dengue hemorrhagic fever in a peripheral blood stem cell transplant recipient. In addition, we review all previous reports of dengue infection in organ transplant recipients.
Highlights
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand a case of dengue hemorrhagic fever (DHF) in a peripheral blood stem cell recipient, and review all previous reports of dengue infection in organ transplant recipients
We present a 16-year c old female patient with acute myeloid r leukemia who received allogeneic peripheral e blood stem cell transplant five months prior to presentation
A 16-year old female was hospitalized at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, due to a high-grade fever without chills, bitemporal headache, generalized myalgia, and nausea one day prior to admission
Summary
Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand a case of DHF in a peripheral blood stem cell recipient, and review all previous reports of dengue infection in organ transplant recipients. We present a 16-year c old female patient with acute myeloid r leukemia who received allogeneic peripheral e blood stem cell transplant five months prior to presentation.
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