Abstract
Dengue fever (DF) is a globally significant infection which causes a range of severe and non-severe clinical manifestations. It is transmitted by mosquitoes of the Aedes genus (primarily Aedes aegypti, but also Aedes albopictus). In this letter, a possible DF epidemic on Thasos Island in Greece, which is described in the Book of Epidemics I of the Corpus Hippocraticum, is presented and analyzed. To my knowledge, it is the first report of DF in the history of medicine.
Highlights
The Dengue fever (DF) epidemic of 1927-1928 in Greece, which first affected the Athens area, was the most recent DF epidemic in Europe transmitted by Aedes aegypti mosquitoes.[3]
This DF epidemic is described in the Book of Epidemics I of the Corpus Hippocraticum.[4]
The patients in the Thasos Island epidemic probably experienced the main symptoms of either DF or dengue hemorrhagic fever/dengue shock syndrome
Summary
Dengue fever (DF) is a globally significant arboviral infection which causes a range of severe to non-severe clinical manifestations.[1,2] It is transmitted by mosquitoes of the Aedes genus (primarily Aedes aegypti, and Aedes albopictus), an insect found in tropical and subtropical regions.[1,2] The DF epidemic of 1927-1928 in Greece, which first affected the Athens area, was the most recent DF epidemic in Europe transmitted by Aedes aegypti mosquitoes.[3].
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