Abstract
We report the use of a biofunctionalized tapered optical fiber based sensor with the integration of graphene oxide (GO) for the detection of Dengue virus (DENV) II E proteins. The tapered region was deposited with GO and functionalized with anti-DENV II E protein IgG antibodies to be tested with different concentrations of DENV II E proteins. The sensor obtained a detection limit of 1 pM with a sensitivity value of 12.77 nm/nM, which was better compared to previously reported studies. The sensor also showed high precision, great selectivity, and high affinity toward E protein with a dissociation constant of K <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</sub> = 1.11 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-9</sup> M <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> . The proposed sensor has undoubtedly exhibited the immense potential of nanomaterial integration for future advancements of dengue diagnostics.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: IEEE Journal of Selected Topics in Quantum Electronics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
