Abstract
Background & aim: Dendritic cell (DC)-based immunotherapy modulates a patient's immune system for recognition and subsequent removal of tumor cells. DC-mediated anticancer therapy has been considered in several studies/ongoing trials for multiple types of cancer. Our aim is to describe the potential and current status of DC-based immunotherapy in oral cancer therapeutics. Materials & methods: An internet-based literature search with relevant search terms from 2012 to 2022 post-screening resulted in 58articles that were considered for systematic review. Results & conclusion: Evaluation of DC based immunotherapyexploiting the critical immune cellsin well-equipped laboratories with adequately trained and skilled experts alongwitha synergistic approach that is affordable and approachable to the patients can prove asan efficientanticancer therapy.
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