Abstract

The thermal behaviour of lyzozyme and human growth hormone (hGH) in aqueous solutions versus pH was studied by DSC experiments. The temperature and enthalpy of denaturation were determined, showing a maximal stability of lyzozyme at pH 4.5, and a large range of pH (5.0–9.0) corresponding to the maximal stability of hGH. These results are in good agreement with those obtained by circular dichroism measurements. The hGH environment was modified by addition of linear or aromatic small molecules and their influence on the parameters of the denaturation was studied.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call