Demonstration of Phytochemicals and In-vitro Antioxidant and Anti-inflammatory activity by methanolic extract of Elettaria cardamomum

Md Shahidul Islam

doi:10.31579/2693-7247/023

Abstract

The existing research study attempts to untie novel avenues for development of the medicinal exercises of Elettaria cardamomum, fashionable known as the “Queen of Spices” and locally recognized as “elaichi”. Its seeds are utilized as abortifacient, acrid, alexiteric, aromatic, sweet, cardiac tonic, cooling, carminative, digestive, diuretic, expectorant, stimulant and also tonic beneficial in the asthma, haemorrhoids, bronchitis, strangury, renal in addition to vesical calculi, anorexia, halitosis, gastropathy dyspepsia as well as burning sensation. The prime goal of this research work is to evaluate antioxidant as well as anti-inflammatory properties of the traditional Bangladeshi medicinal extracts in addition to examine these activities. The aim in present work was to screen the phytochemical profile as well as pharmacological activities of the methanolic extract of this plant’s leaves. To explore pharmacological actions DPPH scavenging test and the HRBC membrane stabilization techniques were done for the antioxidant and also anti-inflammatory test respectively. The pharmacological works revealed that plant extracts might have noteworthy antioxidant effect which is possibly mediated by the inhibition of DPPH free radical which is accountable for oxidation. The IC50 values by the DPPH scavenging test observed for the standard and the leaves were 106.38µg/ml & 594.47µg/ml respectively. There is also moderate anti-inflammatory activity. The IC50 values for anti-inflammatory activity by standard & leaves were 35.04µg/ml and 944.0 µg/ml respectively.

Highlights

The three main important necessities of life are food, clothing and shelter
The pharmacological works revealed that plant extracts might have noteworthy antioxidant effect which is possibly mediated by the inhibition of DPPH free radical which is accountable for oxidation
Phytochemical screening: In Table 3, it is shown that different chemical constituents such as alkaloids, flavonoids, glycosides, phenols, saponins, tannins, terpenoids and triterpenes was present in a Acalyphahispida

Summary

Introduction

The three main important necessities of life are food, clothing and shelter. A host of additional useful manufactured goods are supplied to him by plant kingdom [1]. The knowledge of the drugs has collected over the thousands of years as a result of the man’s curious nature so that nowadays it possess many effectual means of ensuring the health-care [2]. The cardamom oil is effectual as an antioxidant and can increase intensities of glutathione which is a natural antioxidant in our body. The plants that acquire therapeutic properties and exert beneficial the pharmacological effects on animal body are by and large designated as the “Medicinal Plants” [4]. The plants which naturally synthesis and accumulate several secondary metabolites like alkaloids, volatile oils, glycosides, tannins and contain minerals in addition to vitamins possess the medicinal properties [6]. That’s why many medicinal plants have made source of the refined traditional treatment systems that have been in being for the thousands of years and remain to distribute human with innovative medications [8]

Methods

Results

Conclusion