Abstract
Introduction: The recent outbreak of severe acute respiratory syndrome corona virus 2 (SARS‐CoV‐2) and subsequent corona virus disease 2019 (COVID‐19) has created a global health emergency with unparalleled worldwide burden. Passive immunity delivered as anti‐corona virus antibodies from convalescent human plasma may offer a novel therapeutic approach for COVID‐19.
 Aim: The aim of this study is to understand this pandemic and its association to demographic pattern of convalescent plasma donors if any which can help us to find a possible solution to fight against this pandemic.
 Materials and method: This is a retrospective study carried out at Ahmedabad Red Cross from a period of April 2020 to September 2020. The donors are scrutinized on the basis of Age-group, Blood Group, gender and Positive Antibody IgG titre index.
 Result: Among 288 COVID-19 Plasma donor accepted for plasma donation; 278 were males and 7 were females. Majority of the donors belong to age group of 22-27 years of age. B positive blood group was most common encountered in the study. Most donors had SAR-COV-2 antibody titre in range of 2-4.
 Conclusion: In this pandemic convalescent plasma therapy is used on compassionate basis in moderately ill patients and demographic studies help us to know the pattern of infectivity and can help us bring permanent treatment for the same.
 Keywords: Convalescent plasma, blood group, IgG-antibody titre
Highlights
The recent outbreak of severe acute respiratory syndrome corona virus 2 (SARS‐CoV‐2) and subsequent corona virus disease 2019 (COVID‐19) has created a global health emergency with unparalleled worldwide burden
Most donors had SAR-COV-2 antibody titre in range of 2-4. In this pandemic convalescent plasma therapy is used on compassionate basis in moderately ill patients and demographic studies help us to know the pattern of infectivity and can help us bring permanent treatment for the same
In 2014, the use of convalescent plasma collected from patients who had recovered from Ebola virus disease was
Summary
The recent outbreak of severe acute respiratory syndrome corona virus 2 (SARS‐CoV‐2) and subsequent corona virus disease 2019 (COVID‐19) has created a global health emergency with unparalleled worldwide burden. The World Health Organization declared COVID-19 a pandemic on 11 March 2020.[1] India, the first case was reported on 30 Jan. By 9th September, 2020, India has reported 8, 97,394 cases and 73,890 deaths.[2] Treatment recommended by WHO as an empirical treatment during outbreaks.[4] Aim: strategies that have been identified far include To understand any diseases it is important to know about medications uncommonly used in clinical practice. The. Passive immunity delivered as anti‐corona virus antibodies from convalescent human plasma may offer a novel therapeutic approach for COVID‐19. The proposed aim of this study is to understand this pandemic and its association to demographic pattern if any which can help us to find a possible solution to fight against this pandemic
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