Abstract
A compelling and robust body of research suggests that modifiable risk factor reduction could substantially impact risk of Alzheimer's disease (AD) and dementia. The evidence is strongest for cardiovascular risk factors as well as lifestyle risk factors including both physical and cognitive activity while promising data is also emerging for sleep disorders and traumatic brain injury. Cumulatively, the data supports modifiable risk factor reduction at the population-based level, with increasing evidence for multi-domain interventions. Dr. Yaffe will discuss recent trends in dementia, the latest findings, and the public health implications of these strategies.
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