Abstract

Since 1917 fever therapy has become an established procedure in the treatment of dementia paralytica. As early as 1887, Wagner von Jauregg started to use fever-producing agents in the treatment of various psychoses of syphilitic origin. Within recent years many reports have accumulated from all over the world on the use of malaria in the treatment of dementia paralytica, and almost without exception these reports have been favorable. There is still some controversy regarding the mechanism of action of this method, and recently considerable interest has been given to the hypothesis that fever alone is the active agent in bringing about successful therapeutic results. Therefore various mechanical methods of producing fever have been devised in this country and have been employed over a period of about six years. Many of the recent reports on the use of hyperpyrexia in the treatment of neurosyphilis have been very favorable and, in contrast,

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