Dementia increases risk of organ failure and hospital mortality of motorcycle crash‐related hospitalizations in Taiwan: A nationwide population‐based study

Abstract

AbstractBackgroundPrior studies showed dementia is associated with the increased risk of injuries in motorcycle crashes, especially in young onset dementia. However, little is known about the effect of young onset dementia on the risk of organ failure and hospital mortality of motorcycle crash‐related hospitalizations. This study describes the prevalence of organ failure and hospital mortality of motorcycle crash‐related hospitalizations among patients with and without dementia and assesses whether dementia is at higher risk of organ failure and hospital mortality of motorcycle crash‐related hospitalizations.MethodIn this population‐based cohort study, we compared patients with dementia aged 40‐64 years and its age‐ and sex‐ matched participants without dementia when they had the first hospitalization for motor vehicle accident injury (MVAI). Data in this study were obtained from the Taiwan National Health Insurance Research Database entries and Taiwan Police‐reported Traffic Accident Registry between 2006 and 2015. Major outcomes were development of organ failure and hospital mortality in motorcycle crash‐related hospitalizations. Logistic regression with generalized estimating equations were performed to account for hospital clustering effect.ResultIn patients with dementia, the prevalence rates of organ failure and hospital mortality was 6.88% and 4.44%, respectively, which were higher than participants without dementia (3.08% and 2.07%). After adjustment of potential confounders, patients with dementia had a 91% higher risk (95%CI 1.45‐2.51) of organ failure of motorcycle crash‐related hospitalizations than patients without dementia, especially those with respiratory organ failure (adjusted odds ratio [OR]1.96, 95%CI 1.46‐2.63). Similarity, patients with dementia were related with increased risk of hospital mortality (adjusted OR 1.39, 95%CI 1.01‐1.93).ConclusionIn motorcycle crash‐related hospitalizations, the presence of dementia may rise the risk of organ failure and hospital mortality, which warrants the concerns of healthcare providers.