Abstract
The Sri Lanka Journal of Psychiatry (SLJP) is a peer-reviewed, open access journal published bi annually by the Sri Lanka College of Psychiatrists.The Journal publishes original papers, brief reports including case reports and commentaries relevant to psychiatry and allied sciences. The Sri Lanka Journal of Psychiatry is committed to maintaining and conforming to the editorial and ethical standards recommended by the International Committee of Medical Journal Editors.Cover“Perseverance”. These tenacious fishermen in Mannar continue their livelihood despite numerous difficulties. L. N. P. Samarasinghe, Acting Consultant Psychiatrist, Base Hospital Nikaweratiya, Sri Lanka.
Highlights
Snips from the journalsThe endorsement of the Global action plan on the public health response to dementia 2017-2025, by the World Health Organization, marked dementia as a global health burden (1)
This framework provides a comprehensive blueprint for action for policymakers, collaborating with international, regional and national partners in addressing dementia as a public health priority
The article states that research has repeatedly shown that combining cholinesterase inhibitors and memantine has limited success in the treatment of Alzheimer's dementia (AD), and targeting multiple pathways is likely to be required for successful treatment (5)
Summary
The endorsement of the Global action plan on the public health response to dementia 2017-2025, by the World Health Organization, marked dementia as a global health burden (1). Memantine monotherapy is recommended as an option for managing AD for people with moderate AD who are intolerant of or have a contraindication to AChE inhibitors, and for those with severe AD (4) This framework provides a comprehensive blueprint for action for policymakers, collaborating with international, regional and national partners in addressing dementia as a public health priority. Possible interventions through enzymes and metabolites in the kynurenine pathway of tryptophan metabolism in dementia are being currently studied (7).
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