Abstract
The synthetic delta sleep-inducing peptide (DSIP), a monapeptide, was injected intravenously in free moving rabbits (30 nmol/kg). In EEG tests, a significant increase in delta activity occurred within 5 h after injection of DSIP. Motor activity recorded simultaneously showed a slight concomitant decrease. These EEG and behavioral effects confirmed that DSIP also induces, when intravenously injected, orthodox slow wave sleep.
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