Abstract
SARS-CoV-2 has given rise to several variants such as Alpha, Beta, Gamma, Delta and Omicron are the major but not all COVID strains (variants) currently creating concern. The strains avoid antibodies response because of change in structure (mutations in genome) and thus cause disease. The most prevalent and infectious variant identified so far is Delta variant. The spike protein's structural alterations, which make it quick and fit, cause the greater occurrence. The Delta Plus variant was recently found as a variant of the Delta. Furthermore, twin variants of the Delta Plus variant are making their way around the world. Inactivated vaccines (59%), viral vectors (67.74%), and mRNA-based vaccines (77.74%) were found to be efficacious against diseases caused by the SARS-CoV-2 virus. Currently, Community immunization is an efficient strategy to stop COVID- 19; if not, it may persist for a long time and continue to wreak havoc on humanity
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