Delta-9-tetrahydrocannabinol affects consummatory but not appetitive sequence of interspecific aggression in the Mongolian gerbil (Meriones unguiculatus)

Abstract

Mongolian gerbils (Meriones unguiculatus) were tested 1 h after intraperitoneal injections of 5 mg/kg delta-9-tetrahydrocannabinol (THC) for effects of aggressive behavior toward mice. The drug was found to increase latency of attack. Delta-9-THC had no effect on the appetitive sequence of aggression (approach, sniff, chase), but severely inhibited consummatory activity (biting). The results provide further evidence that acute administration of delta-9-THC produces a diminution of aggressive activity.