Abstract
Objectives: To compare the effects of induction/labor to delivery before labor in early onset, severe pre-eclampsia. Methods: Five-year prospective case series. Delivery course and neonatal outcome were examined for 335 women with viable singletons. Results: Induction was successful in 45% of attempts. Women exposed to labor had longer (5.5 days, P<0.0001) admissions to delivery periods and were more often delivered for maternal indications (RR=2.87, 95% CI=1.98–4.16). Their babies were born 1.6 weeks older ( P<0.0001) and 352 g heavier ( P<0.0001) than those delivered before labor. Babies exposed to labor needed intensive care less often (RR=0.4, 95% CI=0.27–0.58), had lower rates of severe hyaline membrane disease (RR=0.26, 95% CI=0.11–0.59) and sepsis (RR=0.56, 95% CI=0.33–0.93), and were discharged earlier ( P<0.0001). Conclusions: Exposure to induction/labor in selected patients is not detrimental to neonatal outcome in early, severe pre-eclampsia.
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