Abstract
Although the importance of oxygen in maintaining functional and morphological integrity of the liver is well established in the experimental animal, little is known about the oxygen supply and utilization in the liver in patients with chronic liver diseases. We have recently developed a spectrophotometric method to estimate the concentration of hemoglobin in the hepatic tissue, the oxygen saturation of hemoglobin in the regional blood, and the hepatic oxygen consumption. In this study, to clarify whether the balance between delivery and use of oxygen in the hepatic tissue is disturbed in chronic liver disease, we investigated hepatic hemodynamics in patients with chronic liver diseases using reflectance spectrophotometry.
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