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Open Accesshttps://doi.org/10.1136/jmedgenet-2018-105930
Copy DOI Journal: Journal of Medical Genetics |  Publication Date: Apr 12, 2019 |
 Citations: 34 |
Affiliation: Heidelberg University, National Center for Tumor Diseases, University Hospital Cologne, University of Ulm, University Hospital Ulm, LMU Klinikum, München Klinik, University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, TU Dresden, German Cancer Research Center, University Hospital Carl Gustav Carus, University Hospital Bonn, University of Bonn, University of Duisburg-Essen, RoMed Kliniken, Rechts der Isar Hospital, Clinical Research Center Kiel, University of Giessen, Universitätsklinikum Gießen und Marburg, Klinikum Ludwigshafen, Kiel University, Krankenhaus Jerusalem, Heinrich Heine University Düsseldorf, Düsseldorf University Hospital, Hannover Medical School, Philipps University of Marburg, University Hospital Schleswig-Holstein, University of Lübeck, Kliniken Essen-Mitte, Charité - Universitätsmedizin Berlin, Goethe University Frankfurt, University Medical Center Hamburg-Eppendorf, Universität Hamburg, Sana Klinikum OffenbachBackgroundFor individuals with ovarian cancer (OC), therapy options mainly depend on BRCA1/2 germline status. What is the prevalence of deleterious somatic variants, that is, does genetic tumour testing identify subgroups...
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