Abstract
Deleted DOI: Management of the Hepatic Lymph Nodes during Resection of Liver Metastases from Colorectal Cancer: A Systematic Review
Highlights
Hepatic lymph node involvement is generally considered a contraindication for liver resection performed for colorectal liver metastases
The primary aims of this review are to determine the role of routine lymphadenectomy or lymphadenectomy indicated by macroscopic nodal involvement; to determine the prognostic significance of hepatic lymph node status in patients undergoing liver resection for colorectal metastases; and whether liver resection is indicated in patients with nodal involvement
There were no randomized controlled trials comparing liver resection with nonsurgical treatments such as chemotherapy in patients with node-positive disease, who were otherwise suitable for liver resection
Summary
Hepatic lymph node involvement is generally considered a contraindication for liver resection performed for colorectal liver metastases. The aim of this review is to assess the role of lymphadenectomy in resection of liver metastases from colorectal cancer. There was no randomized controlled trial which assessed the survival benefit of routine or “selective” lymphadenectomy. Survival rates are low in patients with positive lymph nodes draining the liver irrespective of whether they are detected by routine lymphadenectomy or by macroscopic involvement. Further trials in this patient group are required. The 5-year survival after liver resection varies between 16% and
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