Abstract
Sections from weanling rats sacrificed seven days after receiving small electrolytic lesions in the ventromedial hypothalamus show extensive ventricular dilatation and diminution of the hypothalamic tissue between the wall of the third ventricle and the medial border of the lesion. No comparable changes are evident one to three days after the placement of such lesions. It is suggested that the delayed dissolution of periventricular tissue is due to circulatory impairment elicited by the electrolytic lesion. The question is raised whether the effects of lesions in the ventromedial nucleus could not be due in part at least to such indirect involvement of the periventricular zone.
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