Abstract

Hypertrophic Olivary Degeneration (HOD) is a rare degenerative disease that causes hypertrophy rather than atrophy. The classical presentation of HOD is palatal myoclonus but HOD may also present with tremor, and stiffness in the extremities. In this paper, case report 1 was a man aged 46 years with HOD and Holmes tremor spreading to the head, trunk and bilateral upper and lower extremities after pontine hemorrhage. In case report 2, a 50-year-old man with HOD displayed a sense of stiffness in his left upper and lower extremities after pontine hemorrhage. Although pontine hemorrhage may cause tremor and stiffness in the late period, the development of focused imaging promotes and improves HOD diagnosis. HOD related symptoms can be partially ameliorated by the described medication and rehabilitation regimen.

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