Abstract
Methods 19 patients (m/f-16/3, mean age 59,6± 2,0 years) with history of myocardial infarction ( >1 year) were prospectively enrolled in the study. The CCTA protocol consisted of prospectively gated CTA and DECT. DECT was performed with single-tube 64-row CT in gemstone spectral imaging (GSI) mode with 8 min delay after contrast media injection. Using a 4-point transmurality scale CCTA images were visually assessed for first-pass arterial enhancement deficit and late enhancement in DECT images using iodine distribution maps. Per-segment analysis was performed by 2 observers independently. LGE MRI
Highlights
To compare delayed enhancement Dual-Energy CT (DECT) with cardiac CT angiography (CCTA) and LGE MRI for detection of scars after myocardial infarction and to analyze the possible additive value of delayed DECT as part of CCTA protocol
The CCTA protocol consisted of prospectively gated CTA and DECT
DECT was performed with single-tube 64-row CT in gemstone spectral imaging (GSI) mode with 8 min delay after contrast media injection
Summary
19 patients (m/f-16/3, mean age 59,6± 2,0 years) with history of myocardial infarction ( >1 year) were prospectively enrolled in the study. The CCTA protocol consisted of prospectively gated CTA and DECT. DECT was performed with single-tube 64-row CT in gemstone spectral imaging (GSI) mode with 8 min delay after contrast media injection. Using a 4-point transmurality scale CCTA images were visually assessed for first-pass arterial enhancement deficit and late enhancement in DECT images using iodine distribution maps. Per-segment analysis was performed by 2 observers independently. Was performed after CT (range: 1-3 days) as a reference standard. Test characteristics (sensitivity and specificity, contrast ratio (CR) between normal myocardium and scar tissue) for detection of myocardial scar were calculated both for CCTA and DECT. Per segment agreement between modalities was investigated with Spearman rank correlation coefficient
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