Abstract
There are little published data regarding longer percutaneous drain durations following inflatable penile prosthesis placement; despite this, drain proponents suggest reduced scrotal hematoma formation, while detractors cite the risk of retrograde device seeding. Here, we quantify the outcomes of a multi-institutional cohort with drain durations of 48 hours or greater. Data were collected retrospectively for patients undergoing primary 3-piece inflatable penile prosthesis (IPP) placement who had a postoperative drain placed. Cases were performed by 3 surgeons at 3 high-volume centers between January 1, 2020, and March 31, 2022. It was the routine practice of these surgeons to leave percutaneous drains for an interval of 48hours or greater. R software was used to perform statistical analysis and data visualization. Primary outcomes included rates of infection and hematoma formation. Secondary outcomes included device explantation. During the study period, there were 224 patients meeting initial inclusion criteria. Of these, 15 patients had their drains removed before 48hours, leaving 209 patients for the analysis. Mean drain duration was 67 ± 24.7hours. The mean follow-up interval was 170days. Diabetes mellitus was present in 84 (40%) patients with a mean hemoglobin A1c of 7.2%. Penoscrotal and infrapubic approaches were employed (n = 114 [54.5%] vs n = 95 [45.5%]). Reservoir location was split between space of Retzius and high submuscular, with space of Retzius being more common (n = 164 [78.5%] vs n = 45 [21.5%]). Discrete hematomas were observed in 7 patients, with subsequent operative intervention on 2. Notably, both of these were infection cases. There were 3 (1.4%) total device infections. Revision for noninfection causes was required in 9 (4.3%) patients. Fisher's exact testing demonstrated significant association between hematoma formation and anticoagulation and/or antiplatelet therapy (P = .017). On multivariable logistic regression, only anticoagulation and/or antiplatelet therapy remained significant (P = .035). Maintaining percutaneous closed-suction bulb drains for >48hours following IPP placement is safe. This multi-institutional study fills a hole in IPP perioperative literature, as there have been no previously published data regarding drain durations >48hours. The primary limitations are the retrospective nature and lack of a control population. Maintaining closed-suction bulb drains for >48hours following IPP implantation is safe and associated with infection rates comparable to other modern cohorts and a very low rate of hematoma formation.
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