Abstract
AbstractGroups of rats were exposed to water deprivation and/or food deprivation for 24 h periods. The degree of dehydration obtained was evaluated by weight examinations of the differently treated rats. The plasma and erythrocyte volumes were estimated by the use of i.v. injected isotopes. It was found that on water deprivation the intravascular fluid compartment was reduced relatively more than the total body water content. The blood content in the lungs was estimated from the organ content of isotopes after the rats had been rapidly frozen in liquid nitrogen. When dehydration had caused an 8 % reduction in the total blood volume, the pulmonary blood volume was found to be reduced by 30 %. The pulmonary vascular compartment thus appears to function as an important blood depot in this connection.
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