Dehydrated human amnion/chorion membrane (dHACM) closure in giant perianal condyloma acuminata (Buschke-Löwenstein tumor)

Abstract

Abstract Current gold standard treatment of Buschke-Lowenstein tumor (BLT) is surgical excision. Surgical excision in the perianal region leaves a large area to be covered and bears the risk of poor wound healing as well as infection. Dehydrated human amnion/chorion membrane (dHACM) has been proven to be beneficial in wound closure and has been used in many cases, such as deep ulcers, ophthalmological surgeries, tendon repairs, etc. We report a case of 14-month old boy presented with mass from perianal region since six months prior to visit in Dr Soetomo General Hospital Surabaya. From physical examination, pedunculated exophytic growth with cauliflower-like appearance was found and because of the mass size, the anal opening and the rectum was difficult to be evaluated. CT scan obtained showed heterogenous solid mass with multiple calcification with size of ±7,62 × 6,58 × 3,12 cm in perineal cutaneous and subcutaneous tissue that encases the anus and anorectal area. Surgery was performed to remove the mass and the wound was closed with dHACM. Patient healed well without signs of infection nor excessive scarring. Hence, dHACM could be an excellent option in closing wound post excision in BLT cases.