Abstract
Background/Aim. Carotid stenosis is a risk factor for cognitive impairment. The aim of the study was to evaluate the degree of cognitive impairment in patients with asymp-tomatic and symptomatic carotid stenosis and correlate it with the presence, location, and extent of cerebral ischemic lesions. Methods. A prospective analysis of 180 patients aged 50?70 years, divided into three groups (asymptomatic carotid stenosis, symptomatic carotid stenosis, and controls) was made. We assessed demographic characteristics, vascu-lar risk factors, ultrasound examination of the carotid arter-ies, computerized tomography (CT), magnetic resonance imaging (MRI) of the brain, and neuropsychological testing. Results. The brain CT findings on admission showed is-chemic lesions in the left hemisphere in 13.3% of patients in the asymptomatic group and in 41% of those in the symp-tomatic group. In the right hemisphere, lesions were regis-tered in 10% of the asymptomatic patients and in 46.7% of the symptomatic patients. The difference between groups was statistically significant. The lesion volumes measured on CT and MRI scans were significantly different (p < 0.001) between groups with asymptomatic and symptomatic carot-id stenosis. The degree of cognitive impairment, measured by the Addenbrooke's Cognitive Examination Revised (ACE-R), was significantly different between the groups (p < 0.05), with the most severe deficit in the symptomatic group. Conclusion. Our study has shown that cognitive impairment was more severe in patients with symptomatic carotid stenosis, compared to the patients with asymptomat-ic carotid stenosis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Military Medical and Pharmaceutical Journal of Serbia
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.