Abstract
Multifunctional materials based on a combination of permanent and degradable metals open new perspectives for medical implants combining osseoconductivity and drug-delivery functions which can significantly decrease the number of implants’ revision. In this work, hybrid magnesium-titanium materials were produced via sintering, and the properties of the permanent titanium component before and after the degradation of the temporary magnesium part were evaluated. The changes of chemical composition and mechanical parameters were determined. Loading of hydrogen into the titanium part at room temperature was observed, which deteriorated the mechanical characteristics but could also simultaneously improve the biocompatibility of the permanent titanium implant. The control of degradation of the magnesium part and the modification of the titanium part are required for the development of partly degradable hybrid implants.
Highlights
Metallic implants are generally applied in orthopedic and craniofacial surgery, dental practice and as vascular stents [1]. Due to their high strength, low density, high corrosion resistance, inertness to body environment and excellent integrity to the bone are widely used from hip to wrist applications and as bone fixation materials [2]
The hybrid implant material, which consists of permanent Ti and temporary Mg parts, can be used in the cases when high strength of titanium and bone stimulation by degradation of magnesium are required and/or only partial bone remodelling is expected, as in the case of revision surgery [9]
The variation of color and weight of the titanium part after degradation of magnesium should be taken with significant attention
Summary
Metallic implants are generally applied in orthopedic and craniofacial surgery, dental practice and as vascular stents [1]. The hybrid implant material, which consists of permanent Ti and temporary Mg parts (bimetallic couples), can be used in the cases when high strength of titanium and bone stimulation by degradation of magnesium are required and/or only partial bone remodelling is expected, as in the case of revision surgery [9]. These hybrid materials enable the design of drug-delivery devices, i.e., loading the permanent and/or the temporary parts with drugs
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