Abstract
effects of test stimuli upon isolated human myometrial samplings is dependent upon the ability of this study method to appraise correctly the direct, local response of uterine tissues to the stimulus applied. It has been shown that adequate oxygenation of the muscle strip, control of temperature, pH, ionic composition, and osmolality of the solution in which the tissue is suspended, and a knowledge of the preponderant hormonal stimulus to which the intact uterus was exposed prior to sampling are essential for a correct evaluation of the experimental data obtained.le6 In addition, since the patterns of spontaneous activity displayed by isolated strips of human uterine smooth muscle frequently are not quantitatively
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