Abstract
Testosterone has been implicated in many behaviors related to sexual and reproductive function, but its role in fear responses is unclear. Studies in both humans and animals have linked altered testosterone concentrations to externalizing behaviors like aggression and violence, but less to more internalizing behaviors like fear. Therefore, the current study was designed to investigate the effects of testosterone on innate fear response in male rats. TMT (2,5-dihydo-2,4,5-trimethylthiazoline), a chemical extracted from fox feces, was used to elicit a fear response in the male rats with normal and diminished levels of testosterone. Behavioral indices such as in freezing response, and fear-induced analgesia were monitored in response to TMT. The results demonstrate that deficits in testosterone resulted in a significant increase in the freezing time and fear-induced analgesia. These studies suggest that testosterone decline may have a significant effect on increasing innate fear response and fear-induced enhancement of analgesia in male rats.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
