Deferred and deterred: a review of literature on the impact of deferrals on blood donors

Abstract

BackgroundPotential blood donors can be deferred due to concerns about the impact of the donation on their health or the safety of the blood supply. To date, we lack a comprehensive review of the impact of deferrals on donors and how to mitigate adverse effects.AimsThe aim of this review was to describe the available literature on deferrals, with a focus on the impact of deferrals on donors’ subsequent behaviour, potential reasons for impact and the effectiveness of strategies to improve deferral processes and facilitate donor return.MethodA narrative review of the literature on blood donation deferrals was undertaken.ResultsDeferral rates vary widely across different contexts, with female, younger, first time and minority donors more likely to be ineligible to donate. There is clear evidence that deferrals impact on future donation behaviour, particularly for those deferred at their first donation attempt. Deferral has a negative emotional impact if the deferral is permanent or related to positive test results, while emotions experienced at the time of a temporary deferral are related to donors’ willingness to return.ConclusionAn understanding of the impact of deferrals from the donor perspective provides key information to improve the blood centre practices. There is preliminary evidence of the effectiveness of strategies to retain donors, including enabling the ineligible donor to make an alternative contribution, providing clear information about the deferral, notifying the donor when they can return to donate and addressing practical barriers to return.