Abstract
Defense mechanisms of mice against Exophiala dermatitidis MM-7 were studied using congenitally athymic nude (nu/nu) mice and their heterozygous (nu/+) littermates of BALB/ c background. Each mouse was inoculated intravenously with 106 yeast cells of the fungus and sacrificed at adequate intervals by the 62nd day. Viable cells were counted from the brains, kidneys and livers of the nu/+ and nu/nu mice. Furthermore, various internal organs were examined histopathologically.
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