Abstract

Wireless capsule endoscopy (WCE) has become an irreplaceable tool for diagnosing small intestinal diseases, and detecting the outliers in WCE images automatically remains as a hot research topic. Considering the difficulties in obtaining sufficient labeled WCE data, it is necessary to develop the diagnosis model which works well with only little labeled or even unlabeled training samples. In this paper, a novel semi-supervised deep-structured framework is introduced to solve the problem of outlier detection in WCE images. The key idea of our model is to mine the anomalous graphical patterns existed in the image by analyzing the spatial-scale trends of sequential image regions. Three main contributions are concluded: 1) we integrate a convolutional neural network into long short term memory network, so that the intrinsic differences between outliers and normal instances could be captured. Besides, 2) a assessment model is built by using various signs of anomaly occurrence and fake outliers knowledge learned during the training stage, which enhances the outlier alarm accuracy significantly. Furthermore, 3) a nest-structured training method is proposed, which helps our model achieving efficient training process. Experimental results on the real WCE images demonstrate the effectiveness of our model.

Highlights

  • Small intestinal disease is one of the most common gastrointestinal disorders seen in clinical practice, which including cancer, polyp, infectious inflammation and the like

  • We propose a novel model called Semisupervised Outlier Detection Model, SODM for short

  • In order to cover a variety of small intestinal diseases, we obtain wireless capsule endoscopy (WCE) images with outliers from the public source published in [28], which lists various sorts of small intestinal diseases

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Summary

Introduction

Small intestinal disease is one of the most common gastrointestinal disorders seen in clinical practice, which including cancer, polyp, infectious inflammation and the like. If not diagnosed promptly in the early stage, these diseases are likely to develop into poor long-term prognosis or even death. Early detection of small intestinal disease becomes more crucial. Due to the special position and impressive length of small bowel, it is challenging to utilize wired endoscopes through mouth or anus to the lesion area directly. Owing to the advent of wireless capsule endoscopy (WCE), patients avoid suffering a uncomfortable and lengthy procedure by swallowing this sensor . A typical WCE mainly consists of image sensor, lens, LED and wireless

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