Abstract

Malaria is a disease activated by a type of microscopic parasite transmitted from infected female mosquito bites to humans. Malaria is a fatal disease that is endemic in many regions of the world. Quick diagnosis of this disease will be very valuable for patients, as traditional methods require tedious work for its detection. Recently, some automated methods have been proposed that exploit hand-crafted feature extraction techniques however, their accuracies are not reliable. Deep learning approaches modernize the world with their superior performance. Convolutional Neural Networks (CNN) are vastly scalable for image classification tasks that extract features through hidden layers of the model without any handcrafting. The detection of malaria-infected red blood cells from segmented microscopic blood images using convolutional neural networks can assist in quick diagnosis, and this will be useful for regions with fewer healthcare experts. The contributions of this paper are two-fold. First, we evaluate the performance of different existing deep learning models for efficient malaria detection. Second, we propose a customized CNN model that outperforms all observed deep learning models. It exploits the bilateral filtering and image augmentation techniques for highlighting features of red blood cells before training the model. Due to image augmentation techniques, the customized CNN model is generalized and avoids over-fitting. All experimental evaluations are performed on the benchmark NIH Malaria Dataset, and the results reveal that the proposed algorithm is 96.82% accurate in detecting malaria from the microscopic blood smears.

Highlights

  • Malaria is a disease activated by a type of microscopic parasite transmitted from infected female mosquito bites to humans

  • We evaluate the performance of different deep learning architectures for malaria detection using the NIH Malaria dataset [54]

  • The results reveal that the proposed malaria detection algorithm performs better than the compared deep learning models

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Summary

Introduction

Malaria is a disease activated by a type of microscopic parasite transmitted from infected female mosquito bites to humans. The malaria parasite ruptures the red blood cells in human blood and replicates these parasites to other cells. Light microscopy is a standard method for identifying malaria disease and all its species of parasite by screening films of red blood cells. Like rapid diagnostic tests [2], are used for a prompt parasite-based diagnosis. It is a widely used test with a false positive rate of less than 10%. For examining malaria infection in light microscopy, the glass slide is prepared by applying a drop of blood, which is merged with the Giemsa staining solution to enhance the visibility of parasites in red blood cells under a microscope. An expert microscopist usually takes 20 to 30 min for a careful examination of a single blood film to count the number of infectious cells by inspecting the variations in the shape, color, and size characteristics of red blood cells

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