Abstract

Two-dimensional ultrasound scanning (US) has become a highly recommended examination in prenatal diagnosis in many countries. Accurate detection of abnormalities and correct fetal brain standard planes is the most necessary precondition for successful diagnosis and measurement. In the past few years, support vector machine (SVM) and other machine learning methods have been devoted to automatic recognition of 2D ultrasonic images, but the performance of recognition is not satisfactory due to the wide diversity of fetal postures, shortage of data, similarities between standard planes and other reasons. Especially in the recognition of fetal brain images, the features of fetal brain images such as shape, texture, color and others are very similar, which presents great challenges to the recognition work. In this study, we proposed two main methods based on deep convolutional neural networks to automatically recognize six standard planes of fetal brains. One is a deep convolutional neural network (CNN), and the other one is CNN-based domain transfer learning. To examine the performance of these algorithms, we constructed two datasets. Dataset 1 consists of 30,000 2D ultrasound images from 155 subjects between 16 and 34 weeks. Dataset 2, containing 1,200 images, was acquired from a research participant throughout 40 weeks, which is the entire pregnancy. Experimental results show that the proposed solutions achieve promising results and that the frameworks based on deep convolutional neural networks generally outperform the ones using other classical deep learning methods, thus demonstrating the great potential of convolutional neural networks in this area.

Highlights

  • Ultrasound Scans (US) are widely used in many countries as highly recommended examinations in prenatal diagnosis because they are painless, low-cost, and possible without harmful radiation, and they can be carried out at any stage of pregnancy [1]–[3]

  • The remarkable advantage of deep learning is that this type of algorithm can be extended to difficult problems with relatively complex features, because the features for recognition can be automatically extracted via training

  • In order to determine the effectiveness of the proposed DCNN classifier, we compared the performance of four methods for detecting standard planes from Dataset 1, including three classical machine learning methods which perform outstanding with respect to automatic recognition, such as K-means clustering, support vector machines and radial component-based model (RCM) methods

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Summary

INTRODUCTION

Ultrasound Scans (US) are widely used in many countries as highly recommended examinations in prenatal diagnosis because they are painless, low-cost, and possible without harmful radiation, and they can be carried out at any stage of pregnancy [1]–[3]. During the development of fetal formation, doctors may observe ventricular dilatation, intracranial hematoma, enhanced echo of brain tissue, intracerebral calcification, hydrocephalus, congenital brain atrophy, sub ependymal cyst and other notable features by ultrasound examination [5], [6] These abnormalities require a high level of attention because they may represent the manifestations of intracranial hemorrhage, intracranial infection and ischemichypoxic encephalopathy. Compared with the traditional manual method, automatic recognition of fetal standard planes can reduce the visual fatigue for physicians and enhance the precision of diagnosis. Automatic recognition of fetal brain standard planes from the data acquired by the color Doppler ultrasonic diagnosis apparatus is still a challenge because of practical factors such as low image resolution, motion-caused blur and different fetal positions.

METHODOLOGY
CONVOLUTIONAL NEURAL NETWORK
RESULTS
QUANTITATIVE PERFORMANCE EVALUATION AND COMPARISON
DISCUSSION
CONCLUSION
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