Abstract
BackgroundPropranolol hydrochloride is the first-line agent recommended for the treatment of infantile hemangiomas (IH). Serious adverse effects of propranolol therapy for hemangiomas are infrequent.Case presentationWe report a case presented in deep hypoglycemic coma during his treatment with propranolol for IH. Through our case report and the review of the literature, we aimed to underline the importance of recognizing adverse effects during propranolol therapy. Although propranolol has a long history of safe and effective use in infants and children, pediatricians should be aware that life-threatening adverse effects can happen during propranolol therapy for IH.ConclusionEarly identification of these adverse effects can be of great importance for patient management and prognosis. It must certainly be noted that not just early identification among doctors, but education for parents is crucial.
Highlights
Propranolol hydrochloride is the first-line agent recommended for the treatment of infantile hemangiomas (IH)
Oral propranolol is the first line agent recommended for the treatment of IH
We describe one case receiving treatment with propranolol hydrochloride for his IH, who presented in deep coma
Summary
Propranolol hydrochloride is the first-line agent recommended for the treatment of infantile hemangiomas (IH). Serious adverse effects of propranolol therapy for hemangiomas are infrequent. Through our case report and the review of the literature, we aimed to underline the importance of recognizing adverse effects during propranolol therapy. Oral propranolol is the first line agent recommended for the treatment of IH. Serious adverse effects of propranolol therapy for hemangiomas, which include hypotension, bradycardia, hyperkalemia, bronchospasm and hypoglycemia, are infrequent [7, 12,13,14,15,16]. We describe one case receiving treatment with propranolol hydrochloride for his IH, who presented in deep coma. We aim to highlight the importance of recognizing adverse effects during propranolol therapy for both physicians and caregivers
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