Abstract
Deep brain stimulation affects the pathophysiology of various motor disorders including essential tremor, Parkinson’s disease (PD) and dystonia. The motor deficits from PD have been explained by the firing rate and pattern models. However, due to the variability between patients’ electrophysiology, the pathophysiology for PD is difficult to sparse apart. Neither model can fully explain the spectrum of patient presentations. The localisation and stimulation of various structures including the subthalamic nucleus, globus pallidus internus and ventral intermediate nucleus lead to different effects on the patient’s motor symptoms. This group of targeted structures affects the models of PD in distinct ways. This review aims to explain the models of PD and the effects of stimulation in each structure.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
