Abstract

Deep brain stimulation (DBS) has been available for neurological conditions such as Parkinson's disease and dystonia for over 20 years and is an approved treatment in many countries. DBS for severe mental illness was also first described decades ago, for OCD in 1999 and depression in 2005. However, it is not widely available for these indications as a health-service treatment and remains largely experimental. The reasons include: debate about the best target; acceptability of neurosurgery to psychiatrists and patients; and failures of randomised controlled trials off DBS for depression. This presentation will provide an overview of the controversies in DBS for mental illness, an update of recent evidence concerning brain targets and a discussion of future directions.

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