Abstract
Nausea and vomiting often appear with under various conditions, includ being a common side effect of using anti-neoplastic drugs. Chemotherapy-induced nausea and vomiting (CINV) is a major problem that can often alter the quality of life (QoL) and patient adherence to treatment if left untreated. Aromatherapy peppermint is one form of improvised non pharmacological handling of CINV. This study aims to determine the effectiveness of giving peppermint aromatherapy in reducing CINV in chemotherapy patients.This study was a quasy experiment with a Non Equivalent with Control Group design, with total sample groups of 285 respondents with consecutive technique. Parameters in this study used Rhodes Index Nausea Vomiting and Reching (RINVR). The data were analyzed using Wilcoxon sign rank test as a test of change of nausea scale of pre and post vomiting in experimental group using peppermint aromatherapy and control group. The results of the differences from both groups were tested with mann whitney-u test. Wilcoxon sign rank test analysis, showing differences in the incidence of nausea and vomiting in the control group and intervention group. The result of change of decrease in experimental group value Ï = 0,001 is more significant than control group with value Ï = 0,020. The difference is tested with mann whitney-u test with the result value Ï = 0.002. Aromatherapy works in one’s body by triggering the release of neurotransmitter like enkephalin and endorphin which have analgesic effect and increase the feeling of comfortable and relax. Through inhalation, the fragrance of aromatherapy is transmitted through two ways, first is through limbic system into hypothalamus until pituitary. Second is transmitted through olfactory cortex, into thalamus and then head to neocortex. Through these two ways aromatherapy shall be processed until it creates individual perception
 
 Keywords : CINV, Chemotherapy, Peppermint aromatherapy
Highlights
Vomiting or emesis is a condition due to strong intestinal muscle contraction that it pushes out the content of one’s stomach through their mouth
Nausea and vomiting are side effects which often occur after chemotherapy, and they can stay until 24 hours after the administration of chemotherapy drug (Smeltzer & Bare, 2002)
The frequency of chemotherapy administration can lead to traumatic feeling if the respondent has a record of nausea and vomiting, this will cause the relapse of nausea and vomiting
Summary
Vomiting or emesis is a condition due to strong intestinal muscle contraction that it pushes out the content of one’s stomach through their mouth. Nausea and vomiting often present together in many conditions, including as a common side effect of chemotherapy, well known as chemotherapy-induced nausea and vomiting (CINV) (Pazdur, 2003). The frequency of chemotherapy administration can lead to traumatic feeling if the respondent has a record of nausea and vomiting, this will cause the relapse of nausea and vomiting. Cancer patient experiencing several chemotherapy-induced nausea and vomiting (CINV) may delay their chemotherapy session and refuse their coming treatment due to fear of nausea and vomiting (Mustian, 2011). An inappropriate in experiment group were given peppermint management of nausea and vomiting can aromatherapy oil which is dropped into a hold the chemotherapy process which cotton ball as many as three drops, and they may decrease cancer recovery rate, and were asked for about 5 minutes. Data analysis in this research used Wilcoxon use of peppermint aromatherapy against signed ranks test; the analysis is used to CINV
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