Abstract

BackgroundDelirium is a highly prevalent and morbid syndrome in intensive care units (ICUs). Changing the stressful environment within the ICU via music may be an effective and a scalable way to reduce the burden of delirium.Methods/designThe Decreasing Delirium through Music (DDM) study is a three-arm, single-blind, randomized controlled feasibility trial.Sixty patients admitted to the ICU with respiratory failure requiring mechanical ventilation will be randomized to one of three arms (20 participants per arm): (1) personalized music, (2) non-personalized relaxing music, or (3) attention-control. Music preferences will be obtained from all enrolled participants or their family caregivers. Participants will receive two 1-h audio sessions a day through noise-cancelling headphones and mp3 players. Our primary aim is to determine the feasibility of the trial design (recruitment, adherence, participant retention, design and delivery of the music intervention). Our secondary aim is to estimate the potential effect size of patient-preferred music listening in reducing delirium, as measured by the Confusion Assessment Method for the ICU (CAM-ICU). Participants will receive twice daily assessments for level of sedation and presence of delirium. Enrolled participants will be followed in the hospital until death, discharge, or up to 28 days, and seen in the Critical Care Recovery Clinic at 90 days.DiscussionDDM is a feasibility trial to provide personalized and non-personalized music interventions for critically ill, mechanically ventilated patients. Our trial will also estimate the preliminary efficacy of music interventions on reducing delirium incidence and severity.Trial registrationClinicalTrials.gov, Identifier: NCT03095443. Registered on 23 March 2017.

Highlights

  • Delirium is a highly prevalent and morbid syndrome in intensive care units (ICUs)

  • Our trial will estimate the preliminary efficacy of music interventions on reducing delirium incidence and severity

  • Our study aims to test the feasibility of music listening, and estimate the potential effect size of music listening on delirium, in critically ill patients on mechanical ventilation

Read more

Summary

Discussion

DDM is a feasibility trial for providing personalized and non-personalized music interventions for critically ill, mechanically ventilated patients. Regenstrief Institute did not participate in the design of this study. Results of the trial are intended for publication in a peer-reviewed journal, by the authors, and assistance of professional writers is not expected. Author details 1Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

Background
Methods/design
Findings
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call