Abstract
Anorexia nervosa is accompanied by increased serum revarse triiodothyronine levels and decreased serum triiodothyronine levels. We observed 28 women undergoing gastric plication for morbid obesity and found serum reverse triiodothyronine levels to be significantly decreased (p = 0.018) from a preoperative mean (±SD) of 0.30 (±0.17) to 0.21 (±0.06) ng/ml after weight loss. As all of our subjects were on semistarvation diets and had a significant weight loss (p < 0.001), the observed decrease in reverse triiodothyronine rather than increase (as reported in anorexia nervosa) suggests factors other than weight loss or a semistarvation diet are important in the reverse triiodothyronine increase observed in anorexia nervosa.
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